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Palo Alto Networks: Frontier AI Critical Defense Program + Collaboration with NTT DATA for secure AI adoption

Companies mentioned

Palo Alto Networks worked with Nvidia, Anthropic, and additional organizations to assemble a coalition focused on defending critical infrastructure against AI-enabled cyberattacks. The program framework focused on identifying and mitigating vulnerabilities at network scale, including through network-level controls.

The initiative expanded earlier collaboration involving IBM, Red Hat, Microsoft, Siemens, and Idaho National Laboratory, and added Anthropic, OpenAI, and Mitsubishi. The organizations outlined protection for operational technology (OT), health-care systems, commercial software, and open-source ecosystems from AI-driven exploits.

Participating organizations will work with Palo Alto Networks to identify and mitigate vulnerabilities at network scale. One element cited was the deployment of “virtual patches”—network-level controls designed to neutralize known or newly discovered security weaknesses before software fixes can be developed, tested, and widely deployed.

Palo Alto Networks said work with compute-intensive frontier AI models identified more than 14,000 previously unknown vulnerabilities in open-source software. The company also cited Anthropic’s report that its Claude Mythos Preview Model uncovered more than 23,000 flaws across more than 1,000 open-source projects, while IBM and Red Hat’s Project Lightwell had not disclosed comparable findings. “In the age of frontier AI, the traditional, reactive race to build and deploy software patches before adversaries exploit a flaw is a losing battle,” Palo Alto Networks Chief Product Officer Lee Klarich explained. “Protecting critical infrastructure requires a structural shift from isolated patching to collective, proactive intelligence. Through initiatives like our Frontier AI Critical Defense Program, we can neutralize threats at the network layer before they are weaponized.”

Press release, originally published by Alan Weissberger at techblog.comsoc.org.

Graph Connections

9 companies named across 6 categories, one of 95 sources referencing IBM. Previous coverage: IBM’s Dr. Radha Plumb Discusses Building an AI Control Plane (July).

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