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CISA issues best practices for Microsoft Exchange server security

Source Decision Insights Threat Desk Published November 25, 2025 Companies 3
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3 companies named across 6 categories, one of 185 articles referencing Microsoft. Previous coverage: CISA issues alert on Schneider Electric PowerChute Serial Shutdown vulnerabilities (Nov 2025).

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The Cybersecurity and Infrastructure Security Agency (CISA), collaborating with the National Security Agency and international cybersecurity entities, has published a guide detailing best practices to enhance the security of on-premises (on-prem) Microsoft Exchange servers against exploitation.

The guidance incorporates recommendations addressing vulnerabilities across various components of Exchange Server software, including user authentication mechanisms, network encryption protocols, and application exposure. It emphasizes the need for updated configurations and robust security settings to counter ongoing threat actor activities targeting Exchange environments. The advisory also distinguishes between on-prem and hybrid server deployments and highlights risks associated with unsupported or end-of-life Exchange servers.

The risks identified include potential unauthorized access and exploitation resulting from unprotected or improperly configured Exchange servers. The advisory notes that organizations maintaining outdated Exchange instances may be susceptible to continued intrusion attempts.

Remediation efforts described involve applying the recommended best practices within the published guide and retiring any remaining end-of-life on-prem or hybrid Exchange servers following migration to Microsoft 365 platforms. These steps aim to reduce exposure to known cyber threats.

The advisory concludes by encouraging organizations to integrate the advised security protocols detailed in the Microsoft Exchange Server Best Practices document and to decommission unsupported Exchange servers in hybrid environments to mitigate vulnerabilities.

Blog post, originally published by CISA at cisa.gov.

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